CIDP Disease: Causes, Symptoms, Diagnosis, Treatment

Chronic Inflammatory demyelinating Polyradiculoneuropathy (CIDP) is an uncommon autoimmune disorder. In this condition, your body starts to destroy your own nerve cells. The body attacks the myelin sheaths in CIDP which are the fatty coatings that envelop the nerve-protecting fibers. Scientists believe that CIDP and the more widely known illness Guillain-Barre syndrome are connected. However, CIDP is seen as a chronic, or long-term, condition, whereas GBS is typically more of an acute illness.

CIDP is Categorized as Follows:

• Progressive: Over time, the illness only gets worse.
• Recurring: On and off episodes of symptoms
• Monophasic: The sickness only manifests itself once, for one to three years, and does not reoccur

What Are The Symptoms of CIDP?

The symptoms, although can vary depending on the type of CIDP neurology you have, are generally the same and include:

• Tingling sensations in your arms and legs.
• Gradual deterioration of your legs and limbs.
• Reduced reflexes.
• Unable to walk and balance.
• Lost sensations in your arms and legs, which frequently begins with an inability to feel a pinprick.

What Are The Causes of CIDP?

Damage to nerves that are not located in the brain or spinal cord might result from CIDP (peripheral neuropathy). Multiple nerves are implicated in polyneuropathy. In CIDP, both sides of the body are frequently affected. An aberrant immune reaction is the root cause of CIDP neurology. There are various CIDP triggers. The root cause is frequently unknown. CIDP can develop along with other conditions like:

How is CIDP Diagnosed?

There are several ways to diagnose CIDP, that includes:

How is CIDP Treated?

Early intervention is crucial. It may lessen the risk of nerve injury. This can prevent symptoms from getting worse. Treatment options include:

• Corticosteroids: These drugs reduce inflammation while weakening the immune system.
• Intravenous immunoglobulin (IVIG): To delay your body’s immunological reaction, your doctor may administer shots of concentrated antibodies from healthy individuals.
• Plasma Exchange: In order to suppress your immune system, plasma exchange (PE) involves giving you a portion of blood via an IV.
• Immunotherapy: By preventing your immune system to fight the myelin, these therapies interfere with it.
• Stem Cell Therapy: The goal of stem cell therapy for multiple sclerosis is to eliminate autoreactive immune cells and create a new, self-tolerant immune system in order to treat autoimmune diseases like CIDP.

Both the course of CIDP and the response to treatment might fluctuate substantially between individuals. It is crucial to get therapy as soon as possible because doing so increases your chances of controlling this problem and decreasing symptoms. If you do not obtain CIDP treatment, your symptoms will probably worsen over several years.

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Originally published at https://www.advancells.com on July 26, 2022.